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Wiley, Addiction, 11(106), p. 1978-1988, 2011

DOI: 10.1111/j.1360-0443.2011.03515.x

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The impact of needle and syringe provision and opiate substitution therapy on the incidence of hepatitis C virus in injecting drug users: pooling of UK evidence

Journal article published in 2011 by Katy M. E. Turner, Sharon Hutchinson, Peter Vickerman, Vivian Hope, Noel Craine, Norah Palmateer, Margaret May, Avril Taylor, Daniela De Angelis ORCID, Sheila Cameron, John Parry, Margaret Lyons, David Goldberg, Elizabeth Allen, Matthew Hickman ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

AIMS: To investigate whether opiate substitution therapy (OST) and needle and syringe programmes (NSP) can reduce hepatitis C virus (HCV) transmission among injecting drug users (IDUs). DESIGN: Meta-analysis and pooled analysis, with logistic regression allowing adjustment for gender, injecting duration, crack injecting and homelessness. SETTING: Six UK sites (Birmingham, Bristol, Glasgow, Leeds, London and Wales), community recruitment. PARTICIPANTS: A total of 2986 IDUs surveyed during 2001-09. MEASUREMENT: Questionnaire responses were used to define intervention categories for OST (on OST or not) and high NSP coverage (?100% versus