Published in
Oxford University Press (OUP), Bioinformatics, 23(25), p. 3114-3120
DOI: 10.1093/bioinformatics/btp547
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Bayesian detection of non-sinusoidal periodic patterns in circadian expression data
Journal article published in 2009 by
Darya Chudova,
Alexander Ihler,
Kevin K. Lin 
,
Bogi Andersen,
Padhraic Smyth
,
Bogi Andersen,
Padhraic Smyth
This paper is made freely available by the publisher.
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Abstract
Motivation: Cyclical biological processes such as cell division and circadian regulation produce coordinated periodic expression of thousands of genes. Identification of such genes and their expression patterns is a crucial step in discovering underlying regulatory mechanisms. Existing computational methods are biased toward discovering genes that follow sine-wave patterns.