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Elsevier, Tetrahedron Letters, 52(52), p. 7161-7163, 2011
DOI: 10.1016/j.tetlet.2011.10.125
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Microwave-assisted aza-Prins reaction. Part 2: Straightforward access to 2,6-disubstituted 1-azaadamantanes
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Abstract
Novel symmetrically and unsymmetrically disubstituted 1-azaadamantanes were prepared as a single, chiral diastereomer via double microwave-assisted aza-Prins cyclization in one-pot or sequential reaction format.