Elsevier, Immunity, 4(37), p. 598-600, 2012
DOI: 10.1016/j.immuni.2012.10.005
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The contraction of T cell populations after immune responses is poorly understood. In this issue of Immunity, Singh et al. show that "deletor" T cells regulate the frequency of antigen-specific T cells by competing for shared subthreshold ligands.