In this paper, the design of a low-voltage line driver in a complementary organic technology on foil is presented. The behavior and the variability of circuits are predicted by means of transistor modeling and statistical characterization. The comparison of measurements and simulations of simple digital blocks verifies the effectiveness of the design approach. A transmission-gate based 32-stage line driver and a fully-static one are shown. It is also shown that, based on the statistical organic thin-film transistor (OTFT) characterization, the fully-static logic style is a more suitable choice for implementing line drivers in this technology. The implemented fully-static line driver, which is comprised of 1216 transistors, has the highest transistor count reported for a complementary organic circuit to date. It works at supply voltages from 10 V to as low as 3.3 V, reaching a 1 kHz clock frequency, and occupying an area of 25× 4.7 mm 2 . The drivers are implemented in a technology compatible with that of flat-panel display backplanes and are tested with a QQVGA AMOLED display.