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Elsevier, EBioMedicine, 1(2), p. 37-45, 2015

DOI: 10.1016/j.ebiom.2014.12.002

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Magnetic Resonance Imaging Measures of Brain Structure to Predict Antidepressant Treatment Outcome in Major Depressive Disorder

Journal article published in 2015 by Mayuresh S. Korgaonkar ORCID, William Rekshan, Evian Gordon, A. John Rush, A. John Rush, Leanne M. Williams, Christine Blasey, Stuart M. Grieve ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

•Our study identified biomarkers which provide clinically actionable information in guiding the prescription of ADMs.•The MRI protocols used in our study are routinely used clinically, making this biomarker easy to translate to a clinical setting.•Volumetric measures of the left middle frontal and the right angular gyri can identify a subset of patients who will not remit to three commonly prescribed ADMs.•Our findings contribute three new objective neuroimaging measures to identify non-remitters prior to initiation of treatment.