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Schweizerische Chemische Gesellschaft, CHIMIA, 6(62), p. 471, 2008

DOI: 10.2533/chimia.2008.471

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Expression and amplification of chirality in two-dimensional molecular crystals

Journal article published in 2008 by Karl-Heinz Ernst ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Chirality can be bestowed onto achiral surfaces by adsorption of chiral molecules. This offers a good opportunity to study two-dimensional chiral crystallization phenomena, like lateral resolution of enantiomers or the transfer of handedness from single molecules into mesoscopic ensembles with high resolution by scanning probe microscopy. Induction of homochirality on surfaces via cooperatively amplified interactions in molecular monolayers is a new phenomenon of supramolecular surface chirality. Prochiral molecules will turn into either handedness upon adsorption, but doping with intrinsically chiral molecules breaks this symmetry and induces homochirality. A similar effect is induced by a small enantiomeric excess. The excess molecules provide the chiral bias that becomes amplified into single lattice chirality.