Published in
Elsevier, Carbohydrate Polymers, 2(90), p. 765-772, 2012
DOI: 10.1016/j.carbpol.2012.05.028
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- [www.ncbi.nlm.nih.gov] | PDF
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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S-protected thiolated chitosan: Synthesis and in vitro characterization
Journal article published in 2012 by
Sarah Dünnhaupt,
Jan Barthelmes 
,
Clemens C. Thurner,
Claudia Waldner,
Duangkamon Sakloetsakun,
Andreas Bernkop-Schnürch
,
Clemens C. Thurner,
Claudia Waldner,
Duangkamon Sakloetsakun,
Andreas Bernkop-Schnürch
This paper is available in a repository.
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Abstract
► Synthesis of a novel mucoadhesive thiolated chitosan with protected thiol groups. ► The novel conjugate exhibited promising mucoadhesive features. ► In vitro cytotoxicity of the new conjugate was evaluated and found to be non-toxic. ► Swelling behavior of the polymer decreased with the increase of protection. ► Enhanced cross linking within the novel conjugate resulted in improved stability.