Nature Research, Nature Cell Biology, 5(10), p. 501-502, 2008
DOI: 10.1038/ncb0508-501
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During epithelial–mesenchymal transition (EMT) cells loosen their intercellular contacts and leave the epithelial layer. Three microRNA (miRNA) families modulate EMT upstream of the key cell-adhesion protein E-cadherin, highlighting the potential importance of miRNAs in EMT-dependent processes, such as mesoderm development and tumour metastasis.