Elsevier, Tetrahedron Letters, 52(49), p. 7372-7375
DOI: 10.1016/j.tetlet.2008.10.054
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In this work we show that the intramolecular C-H insertion of diazo-acetamides catalysed by di-rhodium(II) complexes can be highly influenced by the axial ligand on the di-rhodium(II) complex. Axially monocoordinated NHC-Rh(2)(OAc)(4) complexes have a distinct reactivity from the parent Rh(2)(OAc)(4) complex affording the cyclisation products in different rates and selectivities. Surprisingly, a new reaction mode emerged when using these complexes which led to a decarbonylation pathway. (C) 2008 Elsevier Ltd. All rights reserved.