In this paper we address the impact of ACI on dynamic spectrum allocation in multi-radio systems. In particular, we present the benefits of dynamic spectrum allocation by adapting channel bandwidth and distance in order to mitigate ACI in multi-radio mesh networks. Based on our measurement campaign in an indoor mesh testbed, which we extended in order to use adaptive channel width, we evaluate the performance in terms of network throughput. We show that by using channel bandwidth adaptation and antenna separation, the impact of ACI can be significantly reduced. The performed experiments give important insights into ACI in multi-radio cognitive systems which help to develop e.g. better channel assignment algorithms or capacity estimation methods.