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American Association for the Advancement of Science, Science Translational Medicine, 275(7), 2015

DOI: 10.1126/scitranslmed.aaa1957

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Regulation of immune responses to protein therapeutics by transplacental induction of T cell tolerance

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Transplacental modulation of T cell repertoire during immune ontogeny leads to antigen-specific immune tolerance to an immunogenic protein therapeutic.