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Elsevier, Behavioural Brain Research, 2(175), p. 415-419, 2006

DOI: 10.1016/j.bbr.2006.08.034

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Dopamine transporter and D2 receptor binding densities in mice prone or resistant to chronic high fat diet-induced obesity

Journal article published in 2006 by Xu-Feng Huang ORCID, Katerina Zavitsanou, Xin Huang, Yinghua Yu, HongQin Wang, Feng Chen, Andrew J. Lawrence, Chao Deng ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

This study examined the density of dopamine transporter (DAT) and D, receptors in the brains of chronic high-fat diet-induced obese (cDIO), obese-resistant (cDR) and low-fat-fed (LF) control mice. Significantly decreased DAT densities were observed in cDR mice compared to cDIO and LF mice, primarily in the nucleus accumbens, striatal and hypothalamic regions. D, receptor density was significantly lower in the rostral part of caudate putamen in cDIO mice compared to cDR and LF mice. (c) 2006 Elsevier B.V. All rights reserved.