Taylor and Francis Group, Communicative and Integrative Biology, 6(6), p. e25658, 2013
DOI: 10.4161/cib.25658
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Bacterial biofilms are becoming a significant societal problem: biofilms form dental plaque, coat ships causing biofouling, and cling onto medical instruments and implants. Understanding how these surface-bound communities are formed is crucial for the development of suitable strategies for their dispersal. At the heart of a switch that commits Bacilli and related species to form biofilms is a transcriptional regulator called SinR and its multiple antagonists. In this addendum, we discuss an alternative model to account for how one of the antagonists is regulated by controlled proteolysis.