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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 1(54), p. 560-562, 2010

DOI: 10.1128/aac.00762-09

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Nonclonal Emergence of Colistin-Resistant Klebsiella pneumoniae Isolates from Blood Samples in South Korea

Journal article published in 2009 by Ji-Yoeun Suh, Jun Seong Son, Doo Ryeon Chung, Kyong Ran Peck, Kwan Soo Ko ORCID, Jae-Hoon Song
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT In vitro activities of colistin and other drugs were tested against 221 Klebsiella pneumoniae isolates that were collected between 2006 and 2007 in nine tertiary care South Korean hospitals from patients with bacteremia. The clonality of colistin-resistant K. pneumoniae (CRKP) isolates was assessed by multilocus sequence typing (MLST). We found that 15 isolates (6.8%) were resistant to colistin. MLST showed that CRKP isolates were nonclonal, with colistin resistance in K. pneumoniae occurring independently and not by clonal spreading.