ROCOM is a four-loop test facility used for the investigation of coolant mixing in the primary circuit of pressurized water reactors. Recently, a new sensor was developed for an improved visualisation and quantification of the coolant mixing in the downcomer. This new sensor array spans a dense measuring grid and covers nearly the whole downcomer. In the presented work, special emphasis was given to the comparison of the data of this sensor with the results of calculations using the Computational Fluid Dynamics (CFD) code ANSYS CFX. A coolant mixing experiment during natural circulation conditions has been conducted. The underlying scenario of this experiment is based on a boron dilution scenario following a SBLOCA event. The corresponding CFD code solution has been obtained using the Best Practice Guidelines. All main effects observed in the measurement are described by the calculation. The detailed comparison reveals that the calculation underestimates the coolant mixing inside the reactor pressure vessel.The measurement data, boundary conditions of the experiment and facility geometry can be made available to other CFD code users for benchmarking.