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Elsevier, Structure, 9(20), p. 1447-1448, 2012

DOI: 10.1016/j.str.2012.08.013

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Priming the Engine of DNA Synthesis

Journal article published in 2012 by Robyn E. Mansfield, Nicholas E. Dixon ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

In this issue of Structure, Rymer and colleagues present the first crystal structures of a bacterial DnaG primase with bound substrate NTPs and alarmone inhibitors. A thoughtful comparative structural analysis provides important insights into the chemical mechanism of primase.