Elsevier, Structure, 9(20), p. 1447-1448, 2012
DOI: 10.1016/j.str.2012.08.013
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In this issue of Structure, Rymer and colleagues present the first crystal structures of a bacterial DnaG primase with bound substrate NTPs and alarmone inhibitors. A thoughtful comparative structural analysis provides important insights into the chemical mechanism of primase.