Published in
Wiley, Angewandte Chemie, 30(125), p. 7901-7904, 2013
Wiley, Angewandte Chemie International Edition, 30(52), p. 7747-7750, 2013
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DNA Origami as a DNA Repair Nanosensor at the Single-Molecule Level
Journal article published in 2013 by
Maria Tintoré 
,
Isaac Gállego,
Brendan Manning,
Ramon Eritja ,
Carme Fàbrega
,
Isaac Gállego,
Brendan Manning,
Ramon Eritja ,
Carme Fàbrega
This paper is available in a repository.
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Abstract
The folding of DNA molecules by DNA origami is used in a nanosensor to analyze enzymatic DNA repair activity of hAGT. The method uses conformational changes that condition α-thrombin interaction with DNA aptamers, and illustrates the use of DNA origami as a protein recognition biosensor.