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Elsevier, Experimental Gerontology, 4(45), p. 255-268, 2010

DOI: 10.1016/j.exger.2009.12.013

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Experimental approaches to the study of epigenomic dysregulation in ageing

Journal article published in 2010 by Reid F. Thompson, Melissa J. Fazzari, John M. Greally ORCID
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This paper is available in a repository.

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Abstract

In this review, we describe how normal ageing may involve the acquisition of epigenetic errors over time, akin to the accumulation of genetic mutations with ageing. We describe how such experiments are currently performed, their limitations technically and analytically and their application to ageing research.