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MDPI, Sensors, 6(8), p. 3624-3632, 2008

DOI: 10.3390/s8063624

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DNA Extraction Systematics for Spectroscopic Studies

Journal article published in 2008 by Bianca Fogazza Palma, Amanda Borges Ferrari, Herculano da Silva Martinho ORCID, Renata Andrade Bitar, Maria Angélica Gargione Cardoso, Airton A. Martin
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Study of genetic material allows the comprehension the origin of the many biochemical changes that follow diseases, like cancer, promoting the development of early preventive inquiry and more efficient individual treatments. Raman spectroscopy can be an important tool in DNA study, since it allows probe molecular vibrations of genetic material in a fast way. The present work established a systematic way for extract DNA in suitable concentrations and structural integrity allowing studies by Raman spectroscopy or other spectroscopic technique, including bio-analytical sensors for probing genetic alterations.