Targeted LipoCEST Contrast Agents for Magnetic Resonance Imaging: Alignment of Aspherical Liposomes on a Capillary Surface
Journal article published in 2010 by
Dirk Burdinski,
Jeroen A. Pikkemaat,
Mustafa Emrullahoglu,
Francesca Costantini,
Willem Verboom,
Sander Langereis,
Holger Grüll 
,
Jurriaan Huskens
,
Jurriaan Huskens
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Abstract
Searching for orientation: The alignment of aspherical paramagnetic liposomes in a magnetic field makes them attractive contrast agents for magnetic resonance (MR) imaging. The orientation of aspherical liposomes in solution, and the orientation change upon binding to a target surface was determined by using a simple MR technique (see picture).