A complex chromatogram with overlapping peaks is the chromatographer's nightmare. One way to sleep better is to use a statistical method that unravels the chromatogram. Attila Felinger at the University of Veszprém (Hungary) and Maria Chiara Pietrogrande at the University of Ferrara (Italy) present different approaches for decoding complex chromatograms, including a new technique using Fourier analysis and a simple graphical method.