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Wiley, Reviews in Medical Virology, 2(28), p. e1968

DOI: 10.1002/rmv.1968

Wiley, Reviews in Medical Virology, 2(11), p. 103-116, 2001

DOI: 10.1002/rmv.305

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Molecular epidemiology of Respiratory Syncytial Virus

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Human respiratory syncytial virus (RSV) is the major cause of lower respiratory tract disease in infants. It is unusual in that it causes repeated infections throughout life. Despite considerable efforts there is as yet no satisfactory vaccine available. This paper reviews the molecular epidemiology of the RSV and describes the complex genotypic structure of RSV epidemics. The evolution of the virus is discussed, with particular reference to the antigenic and genetic variability of the attachment glycoprotein.