Novel graphene-confined tin nanosheets (G/Sn/G) are constructed using an elaborately designed glucose-assisted chemical protocol. The as-synthesized G/Sn/G are featured with significantly enhanced lithium storage properties when compared with other graphene-based 0D/2D composite nanostructures, disclosing the merits of the 2D/2D composite featured with a surface-to-surface integration formula between graphene and the second 2D phase.