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Lippincott, Williams & Wilkins, NeuroReport, 13(21), p. 902-906, 2010

DOI: 10.1097/wnr.0b013e32833dddb4

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Graded contribution of hippocampus to multifeature binding across temporal delay

Journal article published in 2010 by Lei Zhu, Xiuyan Guo, Li Zheng, Jianqi Li, Mengchao Pei, Zoltan Dienes ORCID, Zhiliang Yang
This paper is available in a repository.
This paper is available in a repository.

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Data provided by SHERPA/RoMEO

Abstract

It is well accepted that all the elements of an episode are combined together by the hippocampus to form an episodic representation. In this study, we further investigated whether the activation pattern of the hippocampus during multifeatural episodic encoding with temporal discontinuities varies with recollective detail in a graded way. Specifically, in the present functional magnetic resonance imaging study, we manipulated two associative features, color and size, and presented the features and the item sequentially. Right hippocampal activation increased with the number of features successfully bound to the item, supporting a graded role of hippocampal activation in bridging temporal discontinuities for integrating multiple episodic features.