Published in
Nature Research, Nature Genetics, 2(45), p. 131-132, 2013
DOI: 10.1038/ng.2522
Links
- ORCID
- Nature Research | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [dash.harvard.edu] | PDF
Tools
Whole exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors
Journal article published in 2013 by
Juliann Chmielecki,
Aimee M. Crago 
,
Mara Rosenberg,
Rachael O'Connor,
Sarah R. Walker,
Lauren Ambrogio,
Daniel Auclair,
Aaron McKenna,
Michael C. Heinrich,
David A. Frank,
Matthew Meyerson
,
Mara Rosenberg,
Rachael O'Connor,
Sarah R. Walker,
Lauren Ambrogio,
Daniel Auclair,
Aaron McKenna,
Michael C. Heinrich,
David A. Frank,
Matthew Meyerson
This paper is made freely available by the publisher.
Full text: Download
Published version:
archiving forbidden
Data provided by 
Abstract
Solitary fibrous tumors (SFTs) are rare mesenchymal tumors. Here, we describe the identification of a NAB2-STAT6 fusion from whole-exome sequencing of 17 SFTs. Analysis in 53 tumors confirmed the presence of 7 variants of this fusion transcript in 29 tumors (55%), representing a lower bound for fusion frequency at this locus and suggesting that the NAB2-STAT6 fusion is a distinct molecular feature of SFTs.