Abscessation of mesenteric lymph nodes and other tissues following Streptococcus equi subsp. equi infection is one of the most insidious complication of strangles. In fact, in a small percentage of cases, the infection may spread from respiratory tract to other organs causing significant source of pain, loss of condition and death. This type of infection, known as “bastard strangles”, is uncommon but has a greater chance of resulting in death. Spreading may be hematogenous, via lymphatic channels or via close association with a septic focus, which results in abscesses in lymph nodes and other organs of the thorax and abdomen. Intermittent colic pain is expression of the abdominal cavity involvement. In the present report we described clinical, instrumental, laboratory and pathological features of a severe colic case, unresponsive to treatment, determined by a Streptococcus equi subsp. equi disseminated infection in a pregnant mare, severely involving the abdominal viscera. Although not usually reported, “Bastard strangles” demonstrated to be a potential sequelae to S. equi subspecies equi infections in the horse also in case of atypical strangles. Prompt recognition of atypical manifestations and sequelae to S. equi are needed to identify, treat, and improve the prognostic outcome.