This paper discusses the benefits of applying Systems Thinking to solving natural resource management problems. It first explains the Systems Thinking concept and briefly outlines its history and emergence in agriculture and natural resource management. A series of case studies are then presented which illustrate practical examples of how Systems Thinking has been used to address real life natural resource management issues. The case studies build on the conclusions of each other by adding additional ways (lessons learnt) of incorporating Systems Thinking into practice to address issues more systemically. The first case study deals with examples of how Systems Thinking facilitated the sharing and integration of disparate sources and forms of knowledge, and making sense of the factors influencing tree density in the tropical savanna region of northern Queensland. The second case study deals with how Systems Thinking has been imbedded in the design and implementation of a research project investigating how to improve financial returns to smallholder tree farmers in the Philippines. The third case study illustrates how Systems Thinking was used to design and facilitate an adaptive rodent management project in Cambodia based on participatory research, development and extension. From these experiences, the authors' highlight a variety of key points that lead to the proposition that Systems Thinking should be 'absorbed' into scientific research, in the same way that statistics, is today an integral part of all sciences. A framework for the application of Systems Thinking is presented to help improve sustainable land management.