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MDPI, Sensors, 2(12), p. 2284-2308, 2012

DOI: 10.3390/s120202284

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Biomarker Discovery by Novel Sensors Based on Nanoproteomics Approaches

Journal article published in 2012 by Noelia Dasilva, Paula Díez ORCID, Sergio Matarraz, María González-González, Sara Paradinas, Alberto Orfao, Manuel Fuentes ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

During the last years, proteomics has facilitated biomarker discovery by coupling high-throughput techniques with novel nanosensors. In the present review, we focus on the study of label-based and label-free detection systems, as well as nanotechnology approaches, indicating their advantages and applications in biomarker discovery. In addition, several disease biomarkers are shown in order to display the clinical importance of the improvement of sensitivity and selectivity by using nanoproteomics approaches as novel sensors.