Impact Journals, Aging, 9(7), p. 616-628, 2015
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As the level of interest in aging research increases, there is a growing number of geroprotectors, or therapeutic interventions that aim to extend the healthy lifespan and repair or reduce aging‐related damage in model organisms and, eventually, in humans. There is a clear need for a manually‐curated database of geroprotectors to compile and index their effects on aging and age‐related diseases and link these effects to relevant studies and multiple biochemical and drug databases. Here, we introduce the first such resource, Geroprotectors (http://geroprotectors.org). Geroprotectors is a public, rapidly explorable database that catalogs over 250 experiments involving over 200 known or candidate geroprotectors that extend lifespan in model organisms. Each compound has a comprehensive profile complete