Elsevier, Tetrahedron Letters, 32(52), p. 4177-4181, 2011
DOI: 10.1016/j.tetlet.2011.06.004
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Sonogashira cross-coupling reactions involving (E)-iodo vinyl stannanes and terminal acetylenes were carried out in the presence of Pd(PPh3)4, CuI and several amines, affording (Z)-tributylstannyl enynes in moderate to good yields (62–91%). Utilizing the catalytic system containing Pd(PPh3)4 (5%), CuI (10%), and TBAOH (40% in aqueous media) as activator, better yields (72–91%) and lower reaction times were achieved.