Medknow Publications, Asian Pacific Journal of Tropical Biomedicine, 3(2), p. 250-252, 2012
DOI: 10.1016/s2221-1691(12)60052-5
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Eight percent of necrotizing soft tissue infections (NSTI) are attributable to group A Streptococci (GAS), and among these, 50% develop streptococcal toxic shock syndrome. The reported mortality associated with NSTI reaches 32%. We present cases of two healthy individuals with minor GAS skin infection which developed to a rapidly progressed NSTI and sepsis despite of the antibiotic treatment, aiming to discuss the lessons learned from the course and management of these patients.