Published in

BMJ Publishing Group, Occupational and Environmental Medicine, 2(48), p. 136-139, 1991

DOI: 10.1136/oem.48.2.136

Links

Tools

Export citation

Search in Google Scholar

Occupational triphenyltin acetate poisoning: a case report.

Journal article published in 1991 by C. Colosio ORCID, M. Tomasini, S. Cairoli, Fo, V. Foà, C. Minoia, M. Marinovich, C. L. Galli
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

A case of triphenyltin acetate (TPTA) poisoning is described. The patient, who had been exposed mainly to cutaneous absorption, showed acute stages of an urticarial eruption, signs of hepatic injury, slight glucose intolerance, and electroencephalographic abnormalities. Concomitant with the highest concentrations of tin in plasma and the peak of tin excretion in urine, neutrophils did not show the normal increase in actin polymerisation after stimulation with a chemotactic peptide (100 nM fMLP). The peak of urinary excretion of tin occurred between the fifth and the sixth day after poisoning; subsequently, the rate of excretion became slow, suggesting biphasic kinetics with the possibility of a cumulative trend.