Published in
Wiley, European Journal of Clinical Investigation, 10(44), p. 940-950, 2014
DOI: 10.1111/eci.12327
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Treatment with Evasin-3 abrogates neutrophil-mediated inflammation in mouse acute pancreatitis
Journal article published in 2014 by
Fabrizio Montecucco 
,
François Mach,
Sébastien Lenglet,
Alain Vonlaufen,
Ana Luiza Gomes Quindere,
Graziano Pelli,
Fabienne Burger,
Katia Galan,
Franco Dallegri ,
Federico Carbone,
Amanda E. Proudfoot,
Nicolas Vuilleumier,
Jean-Louis Frossard
,
François Mach,
Sébastien Lenglet,
Alain Vonlaufen,
Ana Luiza Gomes Quindere,
Graziano Pelli,
Fabienne Burger,
Katia Galan,
Franco Dallegri ,
Federico Carbone,
Amanda E. Proudfoot,
Nicolas Vuilleumier,
Jean-Louis Frossard
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Abstract
Acute pancreatitis is characterized by inflammatory processes affecting not only the pancreas, but also the lung. Here, we investigated timing of leucocyte infiltration and chemokine expression within lung and pancreas during pancreatitis and whether treatments selectively inhibiting chemokines (using Evasins) could improve organ injury.