Evolutionary Psychology studies suggest that women prefer slightly older or similarly aged partners, although to date few hypotheses have been put forth to explain this pattern of choice. Several recent studies have shown changes in male reproductive parameters as a result of increased age. In the current review of medical literature, we found evidence that much older men are more likely to be infertile, women with much older partners are more likely to experience problems during pregnancy, and children of much older men are more likely to have genetic abnormalities. Based on these findings, we suggest that reproducing with much older men does not represent the best reproductive option for women, which would explain the female preference for only slightly older or similarly-aged mates.