Links
- ORCID
- ORCID
- ORCID
- ORCID
- Crossref | PDF
- [europepmc.org] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [link.springer.com] | PDF
Tools
Platypnoea-orthodeoxia syndrome, an underdiagnosed cause of hypoxaemia: four cases and the possible underlying mechanisms
Journal article published in 2015 by
M. Nassif,
H. Lu,
T. C. Konings,
B. J. Bouma 
,
A. Noordegraaf ,
A. Vonk Noordegraaf,
B. Straver,
N. A. Blom,
S. A. Clur,
A. P. C. M. Backx,
M. Groenink,
S. M. Boekholdt ,
D. R. Koolbergen,
M. G. Hazekamp ,
B. J. M. Mulder
and other authors.
,
A. Noordegraaf ,
A. Vonk Noordegraaf,
B. Straver,
N. A. Blom,
S. A. Clur,
A. P. C. M. Backx,
M. Groenink,
S. M. Boekholdt ,
D. R. Koolbergen,
M. G. Hazekamp ,
B. J. M. Mulder
and other authors.
Abstract
Cardiac platypnoea-orthodeoxia syndrome (POS) is a position-dependent condition of dyspnoea and hypoxaemia due to right-to-left shunting. It often remains unrecognised in clinical practice, possibly because of its complex underlying pathophysiology. We present four consecutive patients with POS and patent foramen ovale (PFO) who underwent a successful percutaneous PFO closure, describe the mechanism of their POS and provide a review of the literature.