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Taylor and Francis Group, Nucleosides, Nucleotides and Nucleic Acids, 4-6(29), p. 427-432

DOI: 10.1080/15257771003741174

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How to use the computing environment R to analyze ATP-induced ribonucleotide reductase R1 hexamerization data

Journal article published in 2010 by T. Radivoyevitch ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

R is an object oriented free and open source statistical computing environment. The R package Combinatorially Complex Equilibrium Model Selection is being developed to meet the analysis challenges of ribonucleotide reductase (RNR). An example of its use is given here. This example involves ATP-induced R1 hexamerization dynamic light scattering data that suggests that R1 hexamers have two types of a-sites, one that binds ATP and another that does not (here, R1 is the large subunit of RNR).