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Wiley, Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 4S_Part_10(7), 2011

DOI: 10.1016/j.jalz.2011.05.996

Wiley, Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 4S_Part_1(7), 2011

DOI: 10.1016/j.jalz.2011.05.040

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Localization of Hippocampal Atrophy in Alzheimer's Disease

Journal article published in 2011 by Kaikai Shen, Jurgen Fripp, Fabrice Meriaudeau, Gaël Chételat, Olivier Salvado, Pierrick Bourgeat ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

The hippocampus presents the highest rate of atrophy in the early stage of Alzheimer's disease (AD), with more pronounced neuron loss reported in CA1 and subiculum. The aim of this study is to increase the discrimination power of hippocampal shape analysis between AD and normal controls (NC) by focusing on the subregions with atrophy associated with AD and describing the localized shape changes using statistical shape models (SSMs).