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Lippincott, Williams & Wilkins, The American Journal of Gastroenterology, 5(109), p. 770-772, 2014

DOI: 10.1038/ajg.2014.56

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Genome-wide association study identifies two novel genomic regions in irritable bowel syndrome

Journal article published in 2014 by Elizabeth G. Holliday, John Attia, Stephen Hancock, Natasha Koloski, Mark McEvoy ORCID, Roseanne Peel, Mauro D'Amato, Lars Agréus, Henry Nyhlin, Ann E. Almazar, Anna Andreasson, Yuri A. Saito, Rodney J. Scott, Nicholas J. Talley
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

To the Editor: Irritable bowel syndrome (IBS) is a common, poorly understood gastrointestinal disorder. Although family and twin studies broadly support the existence of a genetic component of IBS risk (1), previous candidate gene association studies had limited capacity to identify novel genes. Genome-wide association studies (GWAS), which have revealed new risk genes for various complex diseases, have not yet been published for IBS.