We measured the phonon dispersions in vanadium along the principal symmetry directions using inelastic x-ray scattering. Our data complement previous results derived from thermal diffuse scattering and clearly reveal several phonon-dispersion anomalies, as well as pronounced variations of the phonon widths. Electronic structure calculations, more specifically, an analysis in terms of Fermi-surface spanning vectors allow the qualitative association of these anomalies with the topology of the Fermi surface, thus highlighting the impor- tance of electron-phonon coupling.