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Springer, Lecture Notes in Computer Science, p. 56-72, 2006

DOI: 10.1007/11905455_3

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From Logical Regulatory Graphs to Standard Petri Nets: Dynamical Roles and Functionality of Feedback Circuits

Journal article published in 2006 by Elisabeth Remy, Paul Ruet, Luis Mendoza, Denis Thieffry, Claudine Chaouiya
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Logical modelling and Petri nets constitute two complemen- tary approaches for the dynamical modelling of biological regulatory net- works. Leaning on a translation of logical models into standard Petri nets, we propose a formalisation of the notion of circuit functionality in the Petri net framework. This approach is illustrated with the modelling and analysis of a molecular regulatory network involved in the control of Th-lymphocyte differentiation.