In the Lower Aptian historical stratotype area (Cassis-La Bédoule, SE France), a geochemical study of the Gargasian (Middle Aptian) marl-limestone alternations of the La Marcouline quarry complements data already obtained from Bedoulian (Early Aptian) sediments there. Nannoconids are the main carbonate producers in both limestones and marls. Although diagenetic minerals, such as ankerite (2.5%) are present in small amounts, the trace-element content of bulk carbonate is very close to that of Nannoconus spp. so geochemical sequences can be defined. The long-term evolution of trace-element content was not affected by diagenetic processes, variations in carbonate mineralogy, or a change of carbonate producers. An increase of around 500 ppm in the strontium content of bulk carbonate occurs between the base of the Cabri zone (late Bedoulian) and the Algerianus zone (late Gargasian). This evolution is linked to fluctuations in seawater Sr/Ca ratios caused by variability in the influx of hydrothermal and river waters, by changes in the ratio of aragonite/calcite production and by shifts in sea level. The eustatic sequence Aptian 4, its parasequences and its key surfaces (sequence boundaries, maximum flooding surface) are clearly reflected in the evolution of the bulk-carbonate contents of manganese.