Published in

Elsevier, Journal of Biotechnology, 1(164), p. 13-18

DOI: 10.1016/j.jbiotec.2012.12.008

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Insertion kinetics of small nucleotides through single walled carbon nanotube

Journal article published in 2013 by A. Clavier, S. Kraszewski, C. Ramseyer, F. Picaud ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

We report molecular dynamic simulations showing that a DNA molecule constituted by five unique bases can be spontaneously inserted into single walled carbon nanotube (SWCNT) in normal conditions (P, T and water environment) depending on the tube radius value. The van der Waals and electrostatic interactions play a central role for the rapid insertion process. Our study shows also that the Guanine molecule inserts the fastest compared to thymine, adenine and cytosine bases, respectively. The differences of insertion time could be exploited for applications concerning for example DNA sequencing