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Wiley, BJOG: An International Journal of Obstetrics and Gynaecology, (121), p. 53-61, 2014

DOI: 10.1111/1471-0528.12843

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Microbicides and their potential as a catalyst for multipurpose sexual and reproductive health technologies

Journal article published in 2014 by Q. Abdool Karim, C. Baxter ORCID, S. Abdool Karim ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

There is an urgent need for technologies to prevent sexual acquisition of HIV infection in young women in sub-Saharan Africa. After two decades of eleven pivotal trials of seven products, antiretroviral-based topical microbicides are showing promise. Building on the CAPRISA 004 trial findings, several trials of new antiviral agents, novel delivery mechanisms and combination/multi-purpose products that address challenges of adherence and meet the sexual and reproductive health needs of men and women, including preventing HIV infection, are underway.