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Taylor and Francis Group, OncoImmunology, 5(2), p. e23887

DOI: 10.4161/onci.23887

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Plasmacytoid dendritic cells and regulatory T cells in the tumor microenvironment

Journal article published in 2013 by Curdin Conrad ORCID, Michel Gilliet
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Tumor-infiltrating plasmacytoid dendritic cells (pDCs) have been associated with poor patient prognosis. We have recently uncovered the ability of pDCs to activate and expand a subset of tumor-infiltrating FOXP3+ regulatory T cells that express inducible costimulator (ICOS), providing new insights into the mechanisms that govern the escape of cancer from immunosurveillance.