Cell Press, Cancer Cell, 4(15), p. 249-251, 2009
DOI: 10.1016/j.ccr.2009.03.012
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Properly designed genome-wide screening strategies can provide new insights into biological processes and/or biomarkers for malignant diseases. In this issue of Cancer Cell, Huang et al. demonstrate that the Krüppel zinc-finger protein ZNF423 is critical for retinoic acid signaling and is likely a favorable prognostic marker for neuroblastoma.