Elsevier, Journal of Surgical Research, 2(176), p. 621-628
DOI: 10.1016/j.jss.2011.10.012
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Chantier qualité GA ; Objectives: We evaluated whether IGL-1, a graft preservation solution containing polyethylene glycol, improves the outcome of small bowel grafts in comparison to the University of Wisconsin (UW) solution in a pig allotransplantation model.[br/] Materials and Methods: Seventeen pigs were randomly allocated to group 1 (n = 10; intestinal allotransplantation with IGL-1) and group 2 (n = 7; allotransplantation with UW). Pigs received no immunosuppression and were sacrificed on postoperative d (POD) 8. Intestinal specimens were obtained from the animal immediately before cold flushing (T0), 2 h after graft reperfusion (T1), and at sacrifice (T2).[br/] Results: Survival rate to POD 8 was 50% in group 1 compared with 16% in group 2 (P