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BioMed Central, Italian Journal of Pediatrics, 1(41), 2015

DOI: 10.1186/s13052-015-0172-0

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Cranial ultrasound findings in late preterm infants and correlation with perinatal risk factors

Journal article published in 2015 by Monica Fumagalli ORCID, Luca Antonio Ramenghi ORCID, Agnese De Carli, Laura Bassi, Pietro Farè, Francesca Dessimone, Silvia Pisoni, Ida Sirgiovanni, Michela Groppo, Alessandra Ometto, Dario Consonni ORCID, Fabio Triulzi, Fabio Mosca
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Background Late preterm infants are the most represented premature babies. They are exposed to a wide spectrum of brain lesions which are often clinically silent, supporting a possible role of cerebral ultrasound screening. Aim of the study is to describe the pattern of cranial ultrasound abnormalities in late preterm infants and to define the need for cranial ultrasound according to perinatal risk factors. Methods A hospital-based cranial ultrasound screening was carried out by performing two scans (at 1 and 5 weeks). Unfavorable cranial ultrasound at 5 weeks was defined as either persistent periventricular hyperechogenicity or severe abnormalities. Results One thousand one hundred seventy-two infants were included. Periventricular hyperechogenicity and severe abnormalities were observed in, respectively, 19.6 % and 1 % of late preterms at birth versus 1.8 % and 1.4 % at 5 weeks. Periventricular hyperechogenicity resolved in 91.3 %. At the univariate analysis gestational age (OR 0.5, 95 % CI 0.32-0.77), Apgar score