Published version of an article in the journal: The Scientific World Journal. Also available from the publisher at: http://dx.doi.org/10.1155/2014/560234 Open Access ; The robust H∞ filtering problem is investigated for a class of complex network systems which has stochastic packet dropouts and time delays, combined with disturbance inputs. The packet dropout phenomenon occurs in a random way and the occurrence probability for each measurement output node is governed by an individual random variable. Besides, the time delay phenomenon is assumed to occur in a nonlinear vector-valued function. We aim to design a filter such that the estimation error converges to zero exponentially in the mean square, while the disturbance rejection attenuation is constrained to a given level by means of the H∞ performance index. By constructing the proper Lyapunov-Krasovskii functional, we acquire sufficient conditions to guarantee the stability of the state detection observer for the discrete systems, and the observer gain is also derived by solving linear matrix inequalities. Finally, an illustrative example is provided to show the usefulness and effectiveness of the proposed design method.