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Bentham Science Publishers, Combinatorial Chemistry & High Throughput Screening, 6(12), p. 580-588

DOI: 10.2174/138620709788681952

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Assays for Eukaryotic Cell Chemotaxis

Journal article published in 2009 by Zac Pujic, Duncan Mortimer, Julia Feldner, Geoffrey J. Goodhill ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Chemotaxis is essential for many biological processes. Much of our understanding of the mechanisms underlying chemotaxis is based on a variety of in vitro assays. We review these assays, dividing them into groups depending on the process used to generate the gradient. We describe how each method works, its strengths and limitations, and provide some information about the kinds of cells that have been studied with each assay.